How it works
With just one cheek swab, Nucleus uncovers your genetic risk for 2000+ conditions — for you and your future kids.

Nucleus comes in two parts:

Part 1
Test kit

Swab your cheek
Testing at home is easy—a simple cheek swab is all it takes to collect your whole-genome DNA sample.

Send your sample
Mail your sample to the lab using the pre-paid envelope included with your kit.

Get your results
Once your sample arrives at the lab, you'll receive your results in about 4-6 weeks.

Part 2
Membership

Nucleus Preview
Find out which diseases you’re a carrier for and how to prevent passing them on.

Nucleus Health
Uncover your genetic risk for 2000+ conditions, including cancers, heart conditions, mental health, and more.

Nucleus AI
Get personalized health tips to reduce your risk for disease in the future.
Testing is easy.
Invest in your future.

*Based on Blueprint Genomics and Natera prices as of June 2024.
How does Nucleus work?
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Nucleus is a whole-genome DNA test that analyzes your DNA for millions of variants that impact you and your future kids' health — from cancers to heart disease.
Testing with Nucleus is easy. A simple at-home cheek swab is all it takes to collect your sample.
What will my results tell me?
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Nucleus provides genetic screenings for 2000+ diseases that you and your future kids could be at risk for. Your results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions.
How long does Nucleus take?
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After you place your order, we'll mail you your Nucleus test kit. Kits typically arrive in 3-5 business days.
After you've collected your sample, you'll be able to send it to the lab using your pre-paid shipping envelope (included with your kit).
After your sample is received by the lab, your DNA will be securely sequenced and analyzed. This typically takes 4-6 weeks, and you'll receive an email as soon as your results are ready.
Note: Actual processing time may vary slightly from patient to patient. It is important to understand that an early result or a result taking longer does not necessarily indicate any problem with the sequencing quality or analysis. The quality and reliability of each Nucleus analysis remain consistent regardless of small differences in the delivery of the results.
Is Nucleus available internationally?
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We currently support customers in the United States, United Arab Emirates, India, Canada, the United Kingdom, Ireland, Australia, Germany, and Italy.
If you live outside of these countries and want to be notified when we support more countries, join the waitlist here.
Does Nucleus accept HSA/FSA payments?
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Yes, Nucleus is HSA/FSA eligible.
To participate, either:
1. Purchase Nucleus with your HSA/FSA card (recommended).
2. Use your invoice (emailed to you after purchase) to request reimbursement.
Nucleus does not provide a Tax ID number, medical diagnosis, diagnostic codes, or letters of medical necessity. Reimbursement is not guaranteed. Please contact your HSA/FSA provider in advance to confirm terms of reimbursement.
Is genetic counseling included?
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Nucleus has partnered with SteadyMD to offer genetic counseling appointments directly in Nucleus. Each one-hour session costs $99 USD (not included with your membership).
How accurate is Nucleus?
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Nucleus' whole-genome sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
Can I download my DNA?
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Yes you can download your DNA from your Account settings page or by selecting "Downloads" from the dropdown menu. You’ll have the option to download your whole genome as VCF, CRAM, SV, CNV, or FASTQ file types. In addition, you can download your whole genome formatted for upload to sites like Promethease or GEDmatch.



























